MPO Muscle Performance Optimizer


  • Augment Strength and Power
  • Stimulate Muscle Protein Synthesis to Build Muscle
  • Decrease Muscle Protein Breakdown (Anti-Catabolic)
  • Boost Aerobic & Anaerobic Endurance and Recovery
  • Neutralize & Buffer Acid in the Muscle
  • Increase the Available Energy in the Muscle
  • Ultimate Natural & Stimulant-Free Performance Enhancer
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Our physician formulated performance enhancer. First dose, every dose, MPO will improve athletic performance by increasing strength, power, and endurance, while preventing muscle breakdown. Trusted by athletes at the highest levels of professional athletics, MPO will revolutionize your performance today. Vegan Friendly.

MPO The Better Pre-Workout

The Performance Enhancer

MPO for Performance

MPO For Performance

MPO is the first performance enhancing supplement that really works and can be safely used by athletes in the NCAA, Professional Sports, and Olympics without risk for testing positive.

You do not need to load MPO. You do not need to cycle on and off MPO.

You can take MPO daily to maximize the MPO effect on strength, power, building muscle and endurance. Or you can take MPO only on exercise days to boost your performance in the gym or during any sporting event.

You will see an improvement in your physical performance with intense exercise with each dose of MPO. This means more reps, more sets, greater strength, quicker recovery between sets and better endurance.

MPO works on Pro’s and the average Joe’s. See why players in the NHL, NFL, UFC, Powerlifting, Soccer, Boxing, and thousands of fitness enthusiasts are using it.

The active ingredients in MPO are all naturally occurring and MPO contains no stimulants.

MPO for Strength

Strength and Power are two of the keystones of athletic performance. You need to maximize your strength every time you train and compete. Whether it is pushing iron, physically dominating your opponent, or even crushing forehands on the court, strength is the pillar of performance.

Every dose of MPO will improve strength and power with high intensity exercise. The ingredients in MPO work synergistically to increase muscle energy, neutralize performance robbing muscle acids, and stimulate mTOR.

What does this do? It produces a noticeable increase in strength and power with each dose. Used over weeks, athletes see significant gains and are able to break through plateaus that previously limited their performance.

“I seemed to get a sudden jolt of strength out of nowhere. I recently started deadlifting again after a long hiatus and although some of it was likely muscle memory, I shattered some then-current PRs on the second week. I noticed these strength effects in other lifts and muscle groups as well. Within two weeks of use, I added at least 5lbs to every dumbbell lift I currently do and 10lbs to every barbell lift I do.”

Htevans – SupplementReviews

MPO for Strength
MPO to Build Muslce

MPO to Build Muscle

Building sport specific muscle is the key for any athlete. Whether it is muscle for sprinting, combat, powering a shot, moving massive weight, or the competing on stage, muscle differentiates the athlete.

Every time you exercise, and every time you are not eating protein, your body starts to breakdown muscle. So you want to maximize muscle protein synthesis (MPS) every chance you get. MPO has 3 ingredients that each have been shown to increase MPS and increase muscle mass. MPO is the first supplement to synergistically combine these ingredients (HMB, HICA, and Phosphatidic Acid) at clinical doses to maximize the MPS effect.

This uniquely allows the natural and vegan compliant ingredients in MPO to boost MPS and stimulate muscle growth with each dose.

MPO for Endurance

It is all about going as hard as you can for as long as you can. Or what coaches like to call “balls to the wall.” The harder and longer you can produce 100% athletic effort, the greater your rewards will be.

And once that 100% effort is spent, the key is how quick will your muscles and aerobic system recover so you can do it again.

MPO will increase the length of time that you can exert 100% effort. It will also improve your recovery and shorten the recovery time needed to do it again. You will see the difference in the gym not only with how much you can lift, but with how many reps and sets you can do. This will drive fitness and improvement more than any other product you have ever taken.

The endurance gains will help with recovery that athletes typically require between sprints (ice hockey, basketball, football, soccer) battles (MMA / boxing rounds), and during longer aerobic activities (running, swimming, tennis).

MPO for Endurance
MPO is Informed Choice Certified

3rd Party Tested

Each time MPO is produced, the product is batch tested by LGC International to ensure that the product is banned substance free. The World Anti-Doping Agency and the United States Anti-Doping Agency have identified and banned over 220 performance enhancing drugs. Athletes that compete on the world stage such as Olympians, Professionals and Collegians are prohibited from using any products that may contain these banned substances.

LGC tests and certifies under their Informed Choice and Informed Sport programs that products wearing their badge are banned substance free.

In addition, to ensure your safety as per FDA and cGMP standards, MPO is further tested heavy metals, yeast and bacterial counts.

We are proud to take the extra step and be part of the Informed Sport programs so that athletes at the highest level can gain the unique advantage of our supplements with peace of mind.

MPO Ingredients & Usage

How to get the most out of your supplements


MPO dosing is based on athlete lean body weight.


  • 100-130 lbs – 1/2 scoop
  • 131-190 lbs – 1 scoop
  • 191-240 lbs – 1.5 scoops
  • 241 lbs and above – 2 scoops

Mix 1 dose of MPO in 6-8 ounces of water in a shaker cup and shake vigorously. If mixed in cool water, some of the ingredients may settle to the bottom of the cup, so, shake in between sips. MPO is designed to drink completely at one time.

For maximum performance benefits, drink MPO about 30 – 45 minutes prior to exercise.

To gain muscle, we recommend taking MPO daily, even on days off. If your goal is to only improve performance, take MPO before competition or training. It is not necessary to cycle on and off MPO.


MPO Muscle Performance Optimizer is not for use by those with pre-existing medical conditions; those taking any medications; those under the age of 18, or women who are contemplating pregnancy, pregnant or nursing. Always consult your physician prior to starting a new supplement, diet and exercise regime. Keep out of reach of children and pets.

Warning California’s Proposition 65

Warning Prop 65

For California Residents

This product may expose you to chemicals which are known to the State of California to cause cancer and birth defects or other reproductive harm. For more information, go to

Muscle Performance Optimizer Nutrition Label

Your Top Questions, Answered

Still Have Questions? We’re Here to Help.

  • What is MPO?

    MPO is the only product on the market that combines 5 ergogenic (high intensity performance aid) ingredients at optimal doses, to maximize athletic performance.

  • What does MPO do?

    MPO increases strength, power, and endurance with each and every dose (that is why we guarantee satisfaction). Those lifting weights will see increased reps, increased maximum loads, and increased sets. Athletes concentrating on explosiveness and power will see improvements in performance. Explosive legs based athletes (ice hockey, sprinters, some football positions) experience increased ‘leg jump’ and faster recovery. Endurance athletes (soccer, ocr, triathlon) see significant gains ‘I can run all day’. Fighting sport athletes see significant endurance and recovery benefit.

  • Is MPO Vegan?

    MPO is vegan compliant and contains no animal based products.

  • Is MPO a preworkout?

    MPO is a performance enhancer (PE). It can be taken prior to a workout or athletic event. If used prior to exercise, drink it 30 – 45 minutes prior.

  • Is MPO produced in cGMP facility?

    Yes, you wouldn’t expect anything less from Dioxyme. MPO is produced in an inspected, certified, Good Manufacturing Practice, state of the art facility. We do this to ensure our quality and your safety.

  • Should I take MPO daily or only on days I exercise?

    If an individual is looking to increase mass, then MPO should be taken daily. For athletes that tend to lose mass during the course of their season, MPO taken daily will help minimize losses. In older individuals who may have lost muscle mass with aging, MPO can be taken daily to minimize muscle loss.

  • Can MPO be mixed with my regular preworkout?

    Absolutely, you can stack MPO with your regular stim type preworkout, especially our E · Energy & Focus.

  • Can I stack MPO with any other Dioxyme products?

    We love to stack MPO with our BCAA Vmino prior to workout. By the way, sports science nutrition timing studies show that BCAA supplementation prior to workout is superior to whey protein prior to workout for muscle gains. So MPO plus BCAA Vmino is the perfect combination. To take it one step further, you can also stack it with E · Energy & Focus.

  • What is batch testing for banned substances?

    Some manufacturers produce products that can contain substances banned from collegiate, professional and Olympic sports. When they produce other products, they may become contaminated and this can lead to a failed test for the athlete.

    Dioxyme protects your safety 2 ways: First we only produce products in a facility that never uses banned ingredients. Second, each time we produce a product, it is tested by independent third party laboratory for banned substances such as steroids, amphetamines, and 220 identified compounds that are prohibited in athletics. This ensures your safety and peace of mind.

Real Reviews

Find Out What Our Customers Have to Say

Customer Reviews

Based on 39 reviews

Honestly it’s an amazing product nothing will happen over night but with a good diet and training hard you see amazing results


Great product!


I’ve only been using the MPO for a week and I can tell a difference in the way I work out. I have more of a pump and I feel more energized throughout the workout than before. Great stuff can wait to see results!

Way to go MPO

Dioxyme MPO gives a great pump and has a great taste.

Works Great and Tastes Good!

I have been using this everyday for about 2.5 weeks now and I’ve definitely felt a strength increase. It’s hard to flavor HICA supplements, but they definitely figured out how - very refreshing semi-sweet lemonade flavor. I will be making this a staple in my arsenal.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.